Procter & Gamble Ends Collaboration on ATI-7505

Procter & Gamble has ended its collaboration with ARYx Therapeutics for development and commercialization of 5-HT4 agonist ATI-7505 for chronic constipation and functional dyspepsia.

ARYx 5HT4 agonist ATI-7505 shows favorable QT profile

ARYx Therapeutic’s 5HT4 agonist ATI-7505 has shown a favorable QT profile. The drug is in Phase II trials for chronic constipation and functional dyspepsia.

Titans Spheramine cell therapy does not meet endpoint

Titan Pharmaceutical’s cell based cell-based therapy for the potential treatment of moderate to advanced Parkinson’s disease has not met endpoints in a Phase IIb trial. The human retinal pigment epithelium (hRPE) cell-based therapeutic is delivered by stereotaxic injection into the brain and produces dopamine specifically to sites deficient in dopamine

Sciele license Addrenex Alpha2 adrenoceptor agonist ADX415

Sciele Pharma has signed an agreement to license Addrenex Pharmaceuticals alpha 2 agonist ADX415 for the Treatment of Hypertension.