Aryx announce favorable QT results with 5HT4 agonist ATI-7505

ARYx Therapeutics have announced that its 5HT4 agonist ATI-7505 had demonstrated a favorable cardiotoxicity profile in a thorough QT study.

Merck publish series of Bradykinin B1 Receptor Antagonists

Merck have published a series of α-Hydroxy Amid Bradykinin B1 Receptor Antagonists

Merck publish series of Histamine H3 inverse agonists

Merck have published a paperon the synthesis and evaluation of a Spiro-isobenzofuranone Histamine H3 Receptor Inverse Agonists