Wyeth publish series of 5-HT1A Receptor/5-HT transporter inhibiors

Wyeth have published a series of dual 5-HT1A /5-HT transporter inhibitors

Actelion publish series of orexin 1/ orexin 2 receptor antagonists

Actelion have published a series of N-glycine-sulfonamides as potent dual orexin 1/ orexin 2 receptor antagonists

Neurocrine Biosciences publish series of adenosine A2A antagonists

Neurocrine Biosciences have published a 2,6-Diaryl-4-acylaminopyrimidine adenosine A2A antagonist

Wyeth publishes series of Neurotensin NTS1 Receptor Partial Agonists

Wyeth have published a series of Neurotensin NTS1 Receptor Partial Agonists

Abbott publish series of Histamine H4 antagonists

Abbott have published a series of 2,4-diaminopyrimidine histamine H4 antagonists

.

Recordati publish series of 5-HT1A Full Agonists

Redordati have published a series of 1,4-dioxane 5-HT1A Full Agonists that are structurally related to WB 4101

GlaxoSmithKline publish series of bombesin receptor subtype 3 agonists

GlaxoSmithKline have published a series of bombesin receptor subtype 3 agonists

Suvens 5-HT6 antagonist effective in Alzheimer models

Data presented at ICAD-2008 show Suven’s 5-HT6 antagonist SUVN-502 to be effective in preclinical models of Alzheimer’s

Merck publish discovery of Nicotinic receptor partial agonist MK-0354

Merck have published the synthesis and preclinical data on nicotinic receptor partial agonist MK-0354

Memory Pharmaceuticals report positive preclinical data for 5-HT6 antagonist

Alzheimer’s Association International Conference show Memory Pharmaceutical’s 5-HT6 antagonist MEM 68626 to demonstate effecacy in animal models of cognition